01 - Whisk together buttermilk and hot sauce in a large bowl. Submerge chicken pieces completely in the marinade. Cover bowl and refrigerate for minimum 1 hour, preferably overnight for maximum flavor penetration.
02 - Combine paprika, garlic powder, onion powder, oregano, thyme, cayenne pepper, black pepper, and salt in a small bowl. Measure out 2 teaspoons of this mixture and set aside specifically for the breading.
03 - In a shallow dish, whisk together all-purpose flour, cornstarch, and the reserved 2 teaspoons of Cajun seasoning until evenly distributed.
04 - Remove chicken from buttermilk marinade, allowing excess liquid to drip off. Press each piece firmly into the seasoned flour mixture, ensuring complete coverage on all sides. Shake off excess coating.
05 - Pour vegetable oil to depth of 2 inches in a large deep skillet or Dutch oven. Heat oil to 350°F, maintaining consistent temperature throughout frying process.
06 - Fry chicken in small batches without overcrowding. Turn pieces occasionally for even cooking. Fry until golden brown and internal temperature reaches 165°F, approximately 12-15 minutes per batch.
07 - Transfer fried chicken to wire rack or paper towels to drain excess oil. Allow meat to rest for 5 minutes before serving to ensure juices redistribute.